Alprostadil cream guide
How to apply prescribed alprostadil cream for erectile dysfunction, with dose, application, and partner precautions.
Alprostadil cream guide
How to apply prescribed alprostadil cream for erectile dysfunction, with dose, application, and partner precautions.
- READ TIME
- 2 min read
- PATHWAY
- Topical (Alprostadil)
€35 · full refund if a doctor doesn't approve it
Licensed EU doctors
Every case read by a registered doctor.
Reply in under 2 hours
On average, in writing, no video call.
Pay only if approved
Not approved? Refunded in full, automatically.
Rated excellent on Trustpilot
4.8 from 540+ independent reviews.
Valid across the EU
E-prescription accepted at EU pharmacies.
On this page
How to use
- Apply 5-30 minutes before activity
Hold the applicator tip as close as possible to the opening at the tip of the penis and apply all the cream. Do not insert the applicator into the opening. The strength is alprostadil 300 mcg.
- Partner precautions
If the partner is pregnant or trying to conceive, use a condom. Wash hands after application.
Medicines and interactions to review. Anticoagulants and other erectile-dysfunction treatments need review before use Use a condom if the partner is pregnant or could become pregnant
Dose schedule
- Short acting, per occasion
Use one single-dose container per occasion, only once in a 24-hour period and no more than 2-3 times per week.
- Review response
If not satisfactory after several proper attempts, discuss with the prescriber.
Side effects
Local effects
Penile or urethral burning, stinging, redness, or minor bleeding. Usually mild and brief.
Partner effects
Partner may experience vaginal burning or itching. Headache or dizziness possible. Priapism rare.
Do not use if
- You are allergic to alprostadil or any ingredient in the applicator
- You have a condition that raises the risk of priapism or a penile condition that has not been reviewed
- A clinician has advised that sexual activity is unsafe because of a heart condition
If any item may apply, do not use the medicine until a clinician has reviewed it.
When to contact your doctor
- An erection lasting 4 hours or longer: seek urgent care
- Severe penile pain, bleeding, rash, or persistent swelling
- The prescribed dose does not provide a satisfactory response after several attempts
Storage
Store in a refrigerator at 2-8°C and do not freeze. An unopened sachet may be kept below 25°C for up to 3 days before use; discard it if unused after that period. Keep it in the original sachet to protect it from light.
What to expect
Alprostadil cream works locally and requires sexual stimulation. Effect within 5-30 minutes lasting about 1-2 hours.
Sources
Questions while you're on treatment?
Message your doctor in your private chat about side effects, doses or anything that worries you. Replies in under 2 hours on average.
- Discreet follow-up in the private chat
- Download your e-prescription
- Renewals reviewed by your doctor
Related guides
Common questions
Who writes the guides?
Do the guides replace my doctor's advice?
Are the guides available in my language?
Ready to start your treatment?
€35 · a doctor replies in under 2 hours on average.
Start consultationNo charge unless a doctor approves your treatment.Pay nothing if a doctor doesn't approve your treatment. Every consultation is fully refundable. How refunds work



