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Dermatology · Medicine

Compounded rosacea spot formula

Compounded rosacea spot formula is prescribed on Hi-Doctor when the licensed doctor considers it appropriate within dermatology.

€40once

Consultation price. The medicine is paid at your pharmacy.

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Compounded rosacea spot formula
About the medicine

What it is and how it works

The spot formula is a magistral preparation combining ivermectin 1%, metronidazole 0.75% and niacinamide 2% in one gel, made by a compounding pharmacy after the prescription is issued. Ivermectin 1% cream and metronidazole 0.75% are each authorised in the EU for the papules and pustules of rosacea.

In the pivotal 12-week trials of ivermectin 1% cream alone, inflammatory lesions fell by about three quarters, and in a 16-week head-to-head trial ivermectin was more effective than metronidazole 0.75%. The compounded combination itself has not been studied as a product; a licensed doctor weighs this before prescribing.

Who it is for

  • Prepared to prescription by a compounding pharmacy
  • Ivermectin and metronidazole, both EU-authorised rosacea actives

Safety summary

Always read the patient leaflet supplied with your medicine. Your doctor reviews risks and interactions before prescribing.

Pricing

One consultation, one clear price

You pay for the doctor's consultation. If a prescription is issued, the medicine is paid at your own pharmacy.

  • Consultation reviewed by an EU-licensed doctor
  • Private follow-up in the in-app chat
  • Full refund if the doctor does not approve
One-off

Dermatology

One-offPhoto review included€40once
  • Consultation reviewed by an EU-licensed doctor
  • Photo review of your skin
  • Electronic prescription if approved
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Full refund if a review is not approved

FAQs

Your questions answered

Compounded rosacea spot formula13 questions
What is the compounded rosacea spot formula?
A gel prepared to prescription by a compounding pharmacy, combining ivermectin 1%, metronidazole 0.75% and niacinamide 2%. Ivermectin 1% cream and metronidazole 0.75% are both EU-authorised rosacea treatments; ivermectin acts on Demodex mites and inflammation, metronidazole on inflammation. The combination itself is compounded rather than a licensed product.
A pea-sized amount once a day to clean, dry skin, spread thinly over the affected areas of the face for a 3-month course. Avoid the eyes and lips. Use a gentle cleanser, a non-comedogenic moisturiser and SPF 50+ in the morning; avoid alcohol-based toners and scrubs.
More questions
Burning, itching or dryness at the application site are the most common effects of both ivermectin and metronidazole, and are usually mild. A temporary flare in the first 2 weeks can happen as mites die off. Stop and contact your doctor for a spreading rash, facial swelling or blistering.
In the pivotal ivermectin 1% trials, lesion counts fell steadily from week 4 with the clearest results at 12 weeks, so plan on 8 to 12 weeks before judging. The doctor checks the diagnosis against acne and perioral dermatitis, asks about pregnancy and breastfeeding, metronidazole allergy, and any oral treatments you are already taking.
Write to your doctor in the private chat in your account: describe what you notice and when it started. The doctor can adjust the plan, pause it or suggest another option. If you have severe symptoms such as difficulty breathing, swelling of the face or chest pain, call 112 or go to an emergency department straight away.
It depends on what you take. List every medicine, supplement and herbal product in the questionnaire, including ones you use only occasionally. The doctor checks for interactions before prescribing, and your pharmacist checks again when you collect Compounded rosacea spot formula.
The doctor can choose another topical option for your skin, adjust how you use it, or refer you to an in-person dermatologist when your skin needs an examination or a treatment that is not prescribed online.
Skin treatments need several weeks to show a change. You can write to your doctor in the private chat about irritation or doubts, and at the end of the course a follow-up consultation with new photos decides whether to continue, change or stop.
Yes. Hi-Doctor runs 100 % online across the EU, so if you live in Madrid you can fill in the questionnaire and receive the medical review without travelling. The electronic prescription issued by the licensed doctor is valid in any EU pharmacy under Directive 2011/24/EU; in Spain it is dispensed directly from the prescription QR.
The doctor reviews its appearance and progression, your history, allergies, current products and clear photos when needed. If your skin needs an in-person examination, the doctor refers you before prescribing.
The private electronic prescription (Receta Médica Privada Electrónica) is issued by a licensed doctor in Spain. It is a PDF carrying every field required by EU Directive 2011/24/EU (patient, prescriber with country of registration, active ingredient, dose), which makes it legally recognised across all 27 EU member states. In Spanish pharmacies it is dispensed from the QR; outside Spain, the pharmacist dispenses the locally marketed equivalent of the same active ingredient.
1) Fill in an online medical questionnaire in about 4 minutes. 2) The plan is €25/month for weight loss or €15/month (billed €45 every 90 days) for hair growth; sexual health is €35 per consultation and a skin consultation is €40. 3) An EU-licensed doctor reviews your case and, if appropriate, issues an electronic prescription. 4) Collect it at any EU pharmacy. If the review is not approved, the applicable fee is refunded in full.
The plan is €25/month for weight loss or €15/month (billed €45 every 90 days) for hair growth; a one-off sexual-health consultation is €35 and a skin consultation covering acne, rosacea, melasma and ageing skin is €40. Each includes a licensed doctor's review and an electronic prescription if approved. If the review is not approved, the applicable fee is refunded in full. Medication is paid for separately at the pharmacy at the price it sets.
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All content on this page has been medically reviewed by: Dr. Alejandro Infante, General medicine, on 25 August 2026. Registration: 080869277 View profile

Pay nothing if a doctor doesn't approve your treatment. Every consultation is fully refundable. How refunds work