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Safety information · Internal patient-safety page

Tretinoin safety summary

Topical tretinoin is a prescription retinoid used for fine lines and rough, sun-damaged skin under medical supervision.

Tretinoin 0.05%

What it's used for

  • Use only as prescribed on the affected skin.
  • Follow the treatment plan and review schedule your doctor gives you.

Most common side effects

  • Dryness, redness, peeling, warmth, burning or stinging.
  • Temporary irritation while the skin adjusts.

Serious side effects: stop and seek care

  • Blistering, crusting, severe swelling or intense persistent irritation.
  • A severe allergic reaction or unexpected change in a skin lesion.

Who should not use it

  • Pregnancy, trying to conceive, or a personal or family history of skin cancer.
  • Active eczema, sunburn, broken skin or allergy to tretinoin or the cream ingredients.

Interactions to flag

  • Do not combine with another retinoid; separate exfoliants, acids, peroxide and depilatory products.
  • Tell the doctor about photosensitising medicines and recent skin procedures.

Message us in the app chat if you notice any of these

  • Irritation is intense despite following the reduced-frequency plan.
  • You become pregnant, start a photosensitising medicine or plan a skin procedure.
AEMPS CIMA: Retirides 0.5 mg/g cream

This page summarises information from the regulator-approved leaflet for reference only. It is not medical advice and does not replace the assessment of an EU-licensed doctor. Your doctor will review your individual history, dose and interactions during your consultation.

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