Safety information · Internal patient-safety page
Adapalene and benzoyl peroxide safety summary
This gel combines a topical retinoid with benzoyl peroxide to treat acne with blackheads, papules and pustules.
What it's used for
- Use only as prescribed on the affected skin.
- Follow the treatment plan and review schedule your doctor gives you.
Most common side effects
- Dryness, redness, scaling, burning or irritation.
- Temporary worsening during the first weeks of treatment.
Serious side effects: stop and seek care
- Facial or eyelid swelling, throat tightness or difficulty breathing.
- Blistering, burns or severe persistent irritation.
Who should not use it
- Pregnancy or trying to conceive.
- Allergy to adapalene, benzoyl peroxide or any ingredient in the gel.
Interactions to flag
- Do not combine with another retinoid or benzoyl-peroxide product.
- Limit sunlight and UV exposure; separate irritating cosmetics from treatment.
Message us in the app chat if you notice any of these
- Irritation becomes painful, blistered or does not settle.
- You become pregnant or start another retinoid treatment.
AEMPS CIMA: Epiduo 1 mg/g + 25 mg/g gel
Back to your consultationThis page summarises information from the regulator-approved leaflet for reference only. It is not medical advice and does not replace the assessment of an EU-licensed doctor. Your doctor will review your individual history, dose and interactions during your consultation.